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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPR1
All Species:
15.15
Human Site:
S519
Identified Species:
30.3
UniProt:
P16066
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16066
NP_000897.3
1061
118919
S519
W
E
D
V
E
P
S
S
L
E
R
H
L
R
S
Chimpanzee
Pan troglodytes
XP_001168194
1047
116964
N503
W
E
E
L
Q
F
G
N
S
E
R
Y
H
K
G
Rhesus Macaque
Macaca mulatta
XP_001085221
1047
116990
N503
W
E
E
L
Q
F
G
N
S
E
R
Y
H
K
G
Dog
Lupus familis
XP_547577
1060
118154
S518
W
E
D
V
Q
P
S
S
L
E
R
H
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P18293
1057
119091
S515
W
E
D
L
Q
P
S
S
L
E
R
H
L
R
S
Rat
Rattus norvegicus
P18910
1057
118933
S515
W
E
D
L
Q
P
S
S
L
E
R
H
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517544
743
84256
I254
K
H
V
N
K
K
R
I
E
L
T
R
Q
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083703
1056
120483
N513
W
E
D
I
H
S
S
N
L
E
K
N
L
R
R
Zebra Danio
Brachydanio rerio
NP_001038402
1067
121798
N525
W
E
D
I
Q
M
S
N
T
E
K
V
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
T511
K
V
D
M
K
D
V
T
V
I
N
L
G
E
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
E544
F
A
K
L
I
E
S
E
K
Q
V
R
G
K
G
Sea Urchin
Strong. purpuratus
P16065
1125
126238
V552
W
K
V
D
W
S
E
V
Q
T
K
A
T
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.2
61.2
91.6
N.A.
90.8
90.8
N.A.
48.5
N.A.
66.1
62.7
N.A.
31.5
N.A.
29.8
35.1
Protein Similarity:
100
73.8
73.8
95
N.A.
94.2
94.2
N.A.
58.6
N.A.
78.7
77.5
N.A.
47.8
N.A.
49
50.8
P-Site Identity:
100
26.6
26.6
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
53.3
46.6
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
66.6
66.6
100
N.A.
100
100
N.A.
6.6
N.A.
80
73.3
N.A.
33.3
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
59
9
0
9
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
67
17
0
9
9
9
9
9
67
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
0
0
0
0
17
0
25
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
34
17
0
0
% H
% Ile:
0
0
0
17
9
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
17
9
9
0
17
9
0
0
9
0
25
0
0
25
0
% K
% Leu:
0
0
0
42
0
0
0
0
42
9
0
9
50
0
9
% L
% Met:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
34
0
0
9
9
0
0
0
% N
% Pro:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
0
9
9
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
50
17
0
50
17
% R
% Ser:
0
0
0
0
0
17
59
34
17
0
0
0
0
0
34
% S
% Thr:
0
0
0
0
0
0
0
9
9
9
9
0
9
0
9
% T
% Val:
0
9
17
17
0
0
9
9
9
0
9
9
0
9
0
% V
% Trp:
75
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _